Duloxetine: Uses, Side Effects, Dosage, Warnings

Because it affects your mood, some people report feeling calm or having their mood boosted while taking the drug. For treating fibromyalgia in children ages 13 to 17 years, the recommended Cymbalta dosage is 30 mg once per day. Your child’s doctor may increase the dosage to 60 mg once per day, based on how well your child responds to the drug. For treating pain from diabetic neuropathy in adults, the recommended dose of Cymbalta is 60 mg once per day. Doses above 60 mg aren’t recommended for treating this condition. It’s not known how often allergic reaction occurred in people taking Cymbalta in clinical trials.

More About Drugs and Medications

In postmarketing experience, fatal outcomes have been reported for acute CYMBALTA overdoses, primarily with mixed overdoses, but also with CYMBALTA only, including 1000 mg of CYMBALTA (approximately 8.3 times the maximum recommended dosage). Signs and symptoms of overdose (CYMBALTA alone or with mixed drugs) included somnolence, coma, serotonin syndrome, seizures, syncope, tachycardia, hypotension, hypertension, and vomiting. Orthostatic hypotension, falls, and syncope have been reported in patients treated with the recommended CYMBALTA dosages. Syncope and orthostatic hypotension tend to occur within the first week of therapy but can occur at any time during CYMBALTA treatment, particularly after dose increases. The risk of falling appears to be related to the degree of orthostatic decrease in blood pressure (BP) as well as other factors that may increase the underlying risk of falls. Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders.

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You may have questions about duloxetine oral capsules and your treatment plan. It’s important to discuss all your concerns with your doctor. Generic drugs are thought to be as safe and effective as the brand-name drug they’re based on. In general, generics usually cost less than brand-name 6 signs alcohol is hurting your relationship drugs. Studies FM-1 and FM-2 compared CYMBALTA 60 mg once daily or 120 mg daily (given in divided doses in Study FM-1 and as a single daily dose in Study FM-2) with placebo. Study FM-2 additionally compared CYMBALTA 20 mg with placebo during the initial three months of a six-month trial.

Generic Name(S): duloxetine

For diabetic neuropathy, fibromyalgia, and musculoskeletal pain, the maximum daily dose is 60 mg. Duloxetine belongs to a group of drugs called selective norepinephrine reuptake inhibitors (SNRIs). It works by increasing the levels of brain chemicals called serotonin and norepinephrine.

1. You may wonder how Cymbalta compares with other medications that are prescribed for similar uses.
2. While a 120 mg/day dose was shown to be effective, there is no evidence that doses greater than 60 mg/day confer any additional benefits.
3. When duloxetine is used to treat generalized anxiety disorder, the pain of diabetic neuropathy, fibromyalgia, or ongoing bone or muscle pain, it is usually taken once a day with or without food.
4. No, Cymbalta isn’t a selective serotonin reuptake inhibitor (SSRI).
5. An interaction is when a substance changes the way a drug works.

For treating fibromyalgia in children, the recommended Cymbalta dosage is 30–60 mg once per day. Children with this condition will usually start treatment by taking 30 mg of Cymbalta once per day. Their doctor may increase the dose to 60 mg once per day if needed. For treating diabetic nerve pain in adults, the recommended starting dosage of Cymbalta is 60 mg once per day. This is also the recommended maintenance (ongoing) dosage, as well as the maximum dosage of the drug, for this purpose. Cymbalta may have several off-label uses in addition to its FDA-approved uses.

This has been established in trials in adult patients with chronic low back pain and chronic pain due to osteoarthritis. Use of CYMBALTA for the treatment of GAD in patients 7 to 17 years of age is supported by one 10-week, placebo-controlled trial (GAD-6). The study included 272 pediatric patients with GAD of which 47% were 7 to 11 years of age (53% were 12 to 17 years of age). CYMBALTA demonstrated superiority over placebo as measured by greater improvement in the Pediatric Anxiety Rating Scale (PARS) for GAD severity score [see Clinical Studies]. Women who discontinue antidepressants during pregnancy are more likely to experience a relapse of major depression than women who continue antidepressants. This finding is from a prospective, longitudinal study that followed 201 pregnant women with a history of major depressive disorder who were euthymic and taking antidepressants at the beginning of pregnancy.

It’s also approved for use in children ages 13 years and older with fibromyalgia. Most of these side effects may go away within a few days or a couple of weeks. But if they become more severe or do not go away, talk with your doctor or pharmacist. The prescription amazon best sellers medicine is also given to help chronic muscle or joint pain, fibromyalgia (a chronic pain disorder), osteoarthritis, and nerve pain caused by diabetic neuropathy. This includes prescription and over-the-counter medicines, vitamins, and herbal products.

Cymbalta is in a class of drugs called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). It works by boosting the amounts of serotonin and norepinephrine, which are natural substances in the brain. Tell your doctor if you also use stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson’s https://soberhome.net/11-natural-remedies-for-erectile-dysfunction-ed/ disease, migraine headaches, serious infections, or prevention of nausea and vomiting. After 2 weeks, their doctor may increase the dosage to 60 mg once per day if needed. The maximum dosage of Cymbalta to treat GAD in children is 120 mg per day. For adults ages 65 years and older, the recommended starting dosage for GAD is 30 mg once per day.

If you’re prescribed a starting dosage of 60 mg per day, you’ll take either 30 mg twice per day or 60 mg once per day. Comparing the prices of brand-name Cymbalta and its generic version, duloxetine, you may notice a significant difference. The estimated cash price for 30 capsules of 60 mg Cymbalta is around $357, while the generic version, duloxetine, can be found for as low as $11 with a free discount card from SingleCare. Coupons and prescription discount cards may be a helpful way to lower the retail prices of medications at participating pharmacies. In any case, it’s always a good idea to shop around and compare different savings options. Duloxetine is used to treat major depressive disorder in adults.

Children younger than 18 years of age should not normally take duloxetine, but in some cases, a doctor may decide that duloxetine is the best medication to treat a child’s condition. Duloxetine (Cymbalta) is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant used for treating depression, anxiety disorder, and pain. Other drugs in this class include milnacipran (Savella), venlafaxine (Effexor), and desvenlafaxine (Pristiq).

Use this medicine (duloxetine capsules) as ordered by your doctor. Ask your pharmacist any questions you have about refilling your prescription. Keep Cymbalta and all medicines out of the reach of children.